The holiday season was the perfect backdrop for a wish come true for so many healthcare workers at Aventura Hospital and Medical Center. Finally, hope was on the horizon as the first doses of the Pfizer-BioNTech COVID-19 vaccine authorized for emergency use by the U.S. Food & Drug Administration began being administered on December 17, 2020 in the hospital’s vaccination clinic headed by Trish Stephens, MD, Chief Medical Officer. The first healthcare heroes to receive the vaccine at Aventura Hospital and Medical Center were Mauricio Danckers, MD, Medical Director, Intensive Care Unit and Daniel Padron, DO, Medical Director, Emergency Services who both are and continue to lead frontline workers in the trenches of the pandemic. As a State of Florida designated teaching facility, the hospital leveraged its Internal Medicine Residency program led by Manuel Suarez, MD, to inoculate fellow healthcare workers. “It is a great honor and privilege to administer this novel vaccine to my colleagues and bring incredible hope to us all. We can end this pandemic together one vaccine at a time.”, shared Anamika Neralla, MD, Internal Medicine Resident and Chief Resident Elect and one of 36 vaccination warriors. By the end of January, Aventura Hospital and Medical Center anticipates administering a total of 3,000 doses in line with CDC guidelines.